Challenges in understanding host genetics and severity of community-acquired pneumonia.

Jordi Solé-ViolánElisa Hernández-BritoJosé Manuel Valencia-GallardoEstefanía Herrera-Ramos Luis BorderíasM Luisa BrionesOlga RajasJorge FreixinetLeonardo LorenteAntoni PayerasJosé FerreresNieves CarbonellNereida González-QuevedoJesus Maria Gonzalez MartinFelipe Rodríguez de CastroCarlos Rodríguez-Gallego

Published in: ERJ open research (2021)

This study found no association of the top two associated FER variants with severity of community-acquired pneumonia. Precise characterisation of phenotypes may be required in order to unravel the genetic mechanisms predisposing to poor outcome in sepsis. https://bit.ly/3jc9SmR.

Keyphrases

community acquired pneumonia
copy number
intensive care unit
acute kidney injury
genome wide
septic shock
gene expression