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USP17 regulates preeclampsia by modulating the NF-κB signaling pathway via deubiquitinating HDAC2.

Aiping LiTing WangShasha ZhouJingjing HanWujia Wu
Published in: Placenta (2023)
Our findings disclosed that USP17 augmented the proliferation and invasion of trophoblast by deubiquitinating HDAC2, which will contribute to novel prospective targets for diagnosing and treating PE.
Keyphrases
  • signaling pathway
  • pi k akt
  • histone deacetylase
  • induced apoptosis
  • epithelial mesenchymal transition
  • early onset
  • lps induced
  • immune response
  • cell proliferation
  • nuclear factor
  • pregnant women
  • inflammatory response