Autoantibodies against the chemokine receptor 3 predict cardiovascular risk.
Felix S MüllerZouhair AherrahrouHanna GrasshoffMarc W HeidornJens Y HumrichLaurence JohansonRédouane AherrahrouTobias ReinbergerAndreas SchulzVincent Ten CateAlejandro Pallares RoblesThomas KoeckSteffen RappTanja LangeLukas BrachaczekFinn LuebberJeanette ErdmannHarald HeideckeKai Schulze-ForsterRalf DechendKarl J LacknerNorbert PfeifferJasmin Ghaemi KerahrodiOliver TüscherAndreas SchwartingKonstantin StrauchThomas MunzelJürgen H ProchaskaGabriela RiemekastenPhilipp S WildPublished in: European heart journal (2023)
In individuals free of autoimmune disease, anti-CXCR3 aAbs were abundant, related to CV end-organ damage, and predicted all-cause death as well as cardiac morbidity and mortality in conjunction with the acceleration of experimental atherosclerosis.