Head-to-head comparison of nasal and nasopharyngeal sampling using SARS-CoV-2 rapid antigen testing in Lesotho.
Niklaus Daniel LabhardtLucia González FernándezBulemba KatendeJosephine MuhairweMoniek BresserAlain AmstutzTracy R GlassMorten RuhwaldJilian A SacksCamille EscadafalMathabo MarekaSekhele M MookoMargaretha de VosKlaus ReitherPublished in: PloS one (2023)
The STANDARD Q Ag-RDT showed high specificity. Sensitivity was, however, below the WHO recommended minimum requirement of ≥ 80%. The high agreement between nasal and nasopharyngeal sampling suggests that for Ag-RDT nasal sampling is a good alternative to nasopharyngeal sampling.