Impact of COVID-19 Related Maternal Stress on Fetal Brain Development: A Multimodal MRI Study.

Vidya RajagopalanWilliam T Reynolds Jeremy ZepedaJeraldine LopezSkorn PonrartanaJohn WoodRafael CeschinAshok Panigrahy

Published in: Journal of clinical medicine (2022)

We report alterations in fetal brainstem structure and global functional fetal brain activity associated with increased maternal stress due to pandemic related disruptions, suggesting altered fetal programming. Long term follow-up studies are required to better understand the sequalae of these early multi-modal brain disruptions among infants born during the COVID-19 pandemic.

Keyphrases

coronavirus disease
sars cov
resting state
white matter
magnetic resonance imaging
birth weight
pregnancy outcomes
gestational age
functional connectivity
cerebral ischemia
pregnant women
computed tomography
respiratory syndrome coronavirus
preterm infants
weight gain
blood brain barrier