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Model-based analysis for the population pharmacokinetics of iberdomide and its major active metabolite in healthy subjects and patients with relapsed and refractory multiple myeloma.

Yiming ChengYongjun XueLu ChenMark MasinPaulo MaciagTeresa PelusoSimon ZhouYan Li
Published in: British journal of clinical pharmacology (2022)
]), combination (in combination with dexamethasone and daratumumab), mild hepatic, or mild and moderate renal impairments. The model can be used to guide the dosing strategy for special patient population and inform future iberdomide study design.
Keyphrases
  • multiple myeloma
  • acute lymphoblastic leukemia
  • case report
  • low dose
  • diffuse large b cell lymphoma
  • current status
  • high intensity