Tolperisone for the Treatment of Acute Muscle Spasm of the Back: Results from the Dose-Ranging Phase 2 STAR Study (NCT03802565).

Srinivas NalamachuJoseph V PergolizziRandall Kaye

Published in: Journal of pain research (2020)

Tolperisone 200 mg TID may be a promising treatment for acute muscle spasm, without the somnolence associated with SMRs. The safety and efficacy of tolperisone should be evaluated in a phase 3 trial.

Keyphrases

liver failure
skeletal muscle
intensive care unit
combination therapy
acute respiratory distress syndrome
botulinum toxin