Atopic dermatitis, inhalant allergy and food allergy: A paediatric approach.
Emine Ece ÖzdoğruMelis GönülalPublished in: Dermatologic therapy (2020)
Food and inhalant allergens have also been identified as potential trigger factors of atopic dermatitis symptoms. Here we aimed to investigate relationships between atopic dermatitis and inhalant-food allergen sensitization in Turkish children with atopic dermatitis. We included 70 patients (42 male, 28 female) with atopic dermatitis and 45 controls (30 male, 15 female) with no atopy, no atopy familial history, no atopy clinical findings no atopic dermatitis. We noted patients' and controls' age, gender, passive smoking exposure, atopy, xerosis, bath water temperature, shower gel type, clothes detergent type, blood hemoglobin, blood eosinophil count, blood eosinophil percent, values of serum immunoglobulin E, serum immunoglobulin A, serum immunoglobulin G, serum immunoglobulin M, results of inhalant allergen, and food allergen testing. We found that nine cases had inhalant allergen sensitization and 21 cases had food allergen sensitization. There were significant relationships between cases and controls in terms of count of eosinophil and percent of eosinophil (P = .008, P = .009, respectively). Humoral and cellular allergen-specific immune responses to food and inhalant allergens can be detected in patients with atopic dermatitis. Accordingly, we believe that blood eosinophil count and percent are more valuable laboratory parameters than serum total IgE for following patients with atopic dermatitis.
Keyphrases
- atopic dermatitis
- immune response
- end stage renal disease
- human health
- allergic rhinitis
- newly diagnosed
- ejection fraction
- chronic kidney disease
- prognostic factors
- early onset
- peripheral blood
- risk assessment
- depressive symptoms
- dendritic cells
- patient reported outcomes
- smoking cessation
- physical activity
- hyaluronic acid
- wound healing