Delineating cerebellar mechanisms in DYT11 myoclonus-dystonia.

Anna SadnickaJoseph M GaleaJui-Cheng ChenThomas T WarnerKailash P Bhatia John C RothwellMark J Edwards

Published in: Movement disorders : official journal of the Movement Disorder Society (2018)

DYT11 is not characterized by a uniform deficit in adaptation. The previously observed large deficit in saccadic adaption is not reflected in an equivalent deficit in limb adaptation in symptomatic body regions. We suggest potential mechanisms at the root of this discordance and identify key research questions that need future study. © 2018 International Parkinson and Movement Disorder Society.

Keyphrases

early onset
current status
risk assessment
climate change
deep brain stimulation