Alterations in atrial ion channels and tissue structure promote atrial fibrillation in hypothyroid rats.

Jianqiang LiZhaorui LiuHongwei ZhaoFengxiang YunZhaoguang LiangDingyu WangXinbo ZhaoJiawei ZhangHai CangYilun ZouYue Li

Published in: Endocrine (2019)

AERP shortening due to altered protein levels of ion channels and atrial structural changes increased the susceptibility to AF in hypothyroidism. Thyroid replacement therapy could prevent electrical and structural remodeling under hypothyroid condition.

Keyphrases

atrial fibrillation
replacement therapy
catheter ablation
left atrial
smoking cessation
oral anticoagulants
left atrial appendage
direct oral anticoagulants
heart failure
percutaneous coronary intervention
protein protein
mitral valve
binding protein
left ventricular
coronary artery disease