AGK (Acylglycerol Kinase) Potentiates Arterial Thrombosis by Affecting Talin-1 and αIIbβ3-Mediated Bidirectional Signaling Pathway.

Peng ZhangHaojie JiangMina YangChanglong BiKandi ZhangDongsheng LiuMeng WeiZheyi JiangKeyu LvChao FangJunling LiuTiantian ZhangYanyan XuJunfeng Zhang

Published in: Arteriosclerosis, thrombosis, and vascular biology (2023)

AGK, through its kinase activity, potentiates platelet activation and arterial thrombosis by promoting Talin-1 Ser425 phosphorylation and affecting the αIIbβ3-mediated bidirectional signaling pathway.

Keyphrases

signaling pathway
protein kinase
pulmonary embolism
pi k akt
epithelial mesenchymal transition
induced apoptosis
tyrosine kinase
oxidative stress