Intraoperative Spinal Cord Stimulation Mitigates Central Sensitization after Spine Surgery in Mice.

Yamamoto SatoshiAlexander DuongAlex KimChengrui HuBlaine WiemersJigong WangJin Mo ChungJun-Ho La

Published in: Spine (2023)

These results demonstrate that spine surgery for unilateral laminectomy induces central sensitization that results in postoperative pain hypersensitivity. Intraoperative SCS after laminectomy may be able to mitigate the development of this hypersensitivity in appropriately selected cases.

Keyphrases

postoperative pain
spinal cord
drug induced
patients undergoing
spinal cord injury
neuropathic pain
high fat diet induced
radiation induced
radiation therapy
metabolic syndrome