The capacity of differentiation of stromal vascular fraction cells into beige adipocytes is markedly reduced in subjects with overweight/obesity and insulin resistance: effect of genistein.

Leonardo Alejandro Rodríguez-López Torre-Villalvazo Iván Gabriela Aleman-EscondrillasAdriana Flores-LópezMartha Guevara-CruzMónica Sánchez-TapiaErik A Torre-AnayaValentín Martínez-LópezSarai Vasquez-ReyesGonzalo M Torres-VillalobosYazmín MacotelaNimbe TorresArmando R Tovar

Published in: International journal of obesity (2005) (2021)

Consumption of genistein may stimulate WAT browning mainly in NW or OIS subjects. Thus, obesity associated with insulin resistance may be considered as a condition that prevents some beneficial effects of some dietary bioactive compounds.

Keyphrases

insulin resistance
high fat diet induced
adipose tissue
metabolic syndrome
high fat diet
skeletal muscle
polycystic ovary syndrome
type diabetes
induced apoptosis
weight loss
bone marrow
weight gain
cell cycle arrest
physical activity
mouse model
body mass index
endoplasmic reticulum stress
oxidative stress