The New Nano-Resuscitation Solution (TPP-MR) Attenuated Myocardial Injury in Hemorrhagic Shock Rats by Inhibiting Ferroptosis.

Lei TanHan SheYi WangYuanlin DuJun ZhangYunxia DuYinyu WuWei ChenBingqiang HuangDuanyang LongXiaoyong PengQinghui LiQingxiang MaoTao LiYi Hu

Published in: International journal of nanomedicine (2024)

The results showed that TPP-MR had a protective effect on myocardial injury in rats with hemorrhagic shock, and its mechanism might be related to improving the mitochondrial function of myocardial cells and inhibiting the process of ferroptosis.

Keyphrases

cell death
cell cycle arrest
signaling pathway
induced apoptosis
left ventricular
contrast enhanced
cardiac arrest
magnetic resonance
pi k akt
cardiopulmonary resuscitation
endoplasmic reticulum stress
heart failure
cell proliferation
drug induced