Evaluation of a Benzodiazepine Immunoassay for Urine Drug Testing in Clinical Specimens.

Mengyuan GeAdekunle AlabiMichael J KelnerRobert L FitzgeraldRaymond T Suhandynata

Published in: The journal of applied laboratory medicine (2024)

The Benzodiazepines II immunoassay demonstrated the greatest clinical and analytical sensitivity compared to the Benzodiazepines Plus and LDT immunoassays. The incorporation of beta-glucuronidase was crucial, as the Benzodiazepines II and LDT immunoassays demonstrated superior clinical sensitivity when compared to the Benzodiazepines Plus immunoassay that does not incorporate a beta-glucuronidase hydrolysis step.

Keyphrases

sensitive detection
emergency department
mass spectrometry
adverse drug