β-escin activates ALDH and prevents cigarette smoke-induced cell death.

Malwina SołtysiakMagdalena Paplińska-GorycaPaulina Misiukiewicz-StępieńPaulina WójtowiczMałgorzata DutkiewiczOliwia Zegrocka-StendelMaria SikorskaDorota DymkowskaLaura Turos-KorgulRafał KrenkeKatarzyna Koziak

Published in: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (2023)

β-escin is an effective ALDH stimulatory and cytoprotective agent and might be useful in the prevention or supportive treatment of tobacco smoke-related diseases.

Keyphrases

cell death
high glucose
diabetic rats
drug induced
cell cycle arrest
mouse model
oxidative stress
signaling pathway
smoking cessation
pi k akt