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Incretin Hormone Secretion in Women with Polycystic Ovary Syndrome: Roles of Obesity, Insulin Sensitivity and Treatment with Metformin and GLP-1s.

Andrea EtruscoMislav MikušAntonio D'AmatoFabio BarraPetar PlaninićTrpimir GolužaGiovanni BuzzaccariniJelena MarušićMara TešanovićAntonio Simone Laganà
Published in: Biomedicines (2024)
The existing research on GLP-1 receptor agonists (GLP-1RAs) has not conclusively established a specific therapeutic use for these drugs. Additionally, the efficacy of the newer generation of GLP-1RAs, particularly in terms of dosage and duration of exposure, warrants more extensive research. Understanding the optimal dosing and treatment duration could significantly enhance the therapeutic use of GLP-1RAs in managing PCOS and its associated conditions.
Keyphrases
  • polycystic ovary syndrome
  • metabolic syndrome
  • type diabetes
  • insulin resistance
  • weight loss
  • adipose tissue
  • weight gain
  • pregnancy outcomes
  • replacement therapy
  • high fat diet induced