Ecto-GPR37: a potential biomarker for Parkinson's disease.

Xavier MoratóPaula Garcia-EsparciaJosep ArgerichFranc LlorensInga ZerrWojciech PaslawskiEva BorràsEduard SabidóUlla E Petäjä-RepoVíctor Fernández-DueñasIsidro FerrerPer SvenningssonFrancisco Ciruela

Published in: Translational neurodegeneration (2021)

GPR37 expression is increased in SN of sporadic PD patients. The ecto-GPR37 peptides are significantly increased in the CSF of PD patients, but not in AD patients. These results open perspectives and encourage further clinical studies to confirm the validity and utility of ecto-GPR37 as a potential PD biomarker.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
peritoneal dialysis
climate change
early onset
cerebrospinal fluid
human health