Resistance to first-generation somatostatin receptor ligands does not impair the results of gamma knife radiosurgery in acromegaly.

Marco Losa Eugenia ResminiLina R BarzaghiLuigi AlbanoMichele BailoSusan M WebbPietro Mortini

Published in: Clinical endocrinology (2021)

We demonstrate for the first time that the responsiveness to SRL has no effect on the probability to obtain remission of acromegaly after GKRS. The remission of disease occurred more frequently in patients who had lower GH and IGF-1 levels before GKRS.

Keyphrases

growth hormone
disease activity
ulcerative colitis
brain metastases
binding protein
rheumatoid arthritis
systemic lupus erythematosus
small cell lung cancer
neuroendocrine tumors
cell proliferation