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Integration of GWAS Summary Statistics and Gene Expression Reveals Target Cell Types Underlying Kidney Function Traits.

Yong LiStefan HaugPascal SchlosserAlexander TeumerAdrienne TinCristian PattaroAnna KottgenMatthias Wuttke
Published in: Journal of the American Society of Nephrology : JASN (2020)
Integration of GWAS statistics of kidney function traits and gene expression data identified relevant tissues and cell types, as a basis for further mechanistic studies to understand GWAS loci.
Keyphrases
  • gene expression
  • genome wide
  • dna methylation
  • single cell
  • cell therapy
  • genome wide association study
  • stem cells
  • mesenchymal stem cells
  • big data
  • case control