HIF-1α promotes astrocytic production of macrophage migration inhibitory factor following spinal cord injury.
Huifei HaoYuxuan HouAicheng LiLi NiuShaolan LiBingqiang HeXingyuan ZhangHonghua SongRixin CaiYue ZhouChun YaoYongjun WangYingjie WangPublished in: CNS neuroscience & therapeutics (2023)
SCI-induced activation of HIF-1α is able to promote MIF production from astrocytes. Our results have provided new clues for SCI-induced production of DAMPs, which may be helpful for clinical treatment of neuroinflammation.