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Main features of ischemic stroke in patients with acute immune-mediated thrombotic thrombocytopenic purpura.

Addolorata TrumaIlaria ManciniPasquale AgostiAndrea ArtoniJuri Alessandro GiannottaBarbara FerrariPasqualina De LeoFlora Peyvandi
Published in: Thrombosis research (2024)
23 % of patients presenting with neurological manifestations at their first acute TTP episode, showed brain IS. As expected, MRI showed higher sensitivity in detecting ischemic lesions underscoring its usefulness over CT in this setting. An unexpected prevalence of non-lacunar and multifocal stroke patterns warrants further investigation. Cardiovascular risk factors and iTTP-related clinical and laboratory parameters were similarly distributed in patients with and without IS.
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