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Distinct Serum and Vitreous Inflammation-Related Factor Profiles in Patients with Proliferative Vitreoretinopathy.

Yao NiYingyan QinZijing HuangFangyuan LiuShaochong ZhangShaochong Zhang
Published in: Advances in therapy (2020)
Our study found that none of the circulating inflammation-related factors were changed in PVR or RRD patients, indicating the absence of a system inflammatory biomarkers to predict the development of proliferative vitreoretinopathy. As a supplement to previous research, the concentrations of PDGF-AA, TGF-α, VEGF, IL-6, IL-8, and TNFβ were significantly upregulated in the vitreous of PVR patients. These factors should be considered for preventing PVR.
Keyphrases
  • end stage renal disease
  • oxidative stress
  • ejection fraction
  • newly diagnosed
  • peritoneal dialysis
  • prognostic factors
  • rheumatoid arthritis