Login / Signup

The Interplay between HGF/c-met Axis and Nox4 in BRAF Mutated Melanoma.

Francesca BerettiFrancesca FarnetaniLuca Reggiani BonettiLuca FabbianiManuela ZavattiAntonino MaioranaGiovanni PellacaniTullia Maraldi
Published in: International journal of molecular sciences (2021)
The observed correlation suggests an interplay between c-met and Nox4 in promoting the onset of metastasis. This study suggests that Nox4 inhibitors could be associated to the current therapy used to treat melanoma patients with BRAF mutations.
Keyphrases
  • reactive oxygen species
  • wild type
  • tyrosine kinase
  • metastatic colorectal cancer
  • skin cancer