Glycogen synthase kinase-3 beta inhibitors protectagainst the acute lung injuries resulting from acute necrotizing pancreatitis.

Hongzhong Jin Xiaojia Yang Kailiang Zhao Liang Zhao Chen Chen Jia Yu

Published in: Acta cirurgica brasileira (2019)

Inhibition of GSK-3β weakens acute lung injury related to ANP via the inhibitory function of NF-κB signaling pathway. Different kinds of GSK-3β inhibitors have different effects to ANP acute lung injury.

Keyphrases

signaling pathway
pi k akt
lps induced
liver failure
lipopolysaccharide induced
respiratory failure
drug induced
epithelial mesenchymal transition
aortic dissection
inflammatory response
induced apoptosis
tyrosine kinase
oxidative stress
extracorporeal membrane oxygenation