Periosteum-inspired in situ CaP generated nanocomposite hydrogels with strong bone adhesion and superior stretchability for accelerated distraction osteogenesis.

Tengfei LouKai ChenQiyu LuoChangsheng LiuYuan YuanCunyi Fan

Published in: Biomaterials research (2022)

This periosteum-inspired nanocomposite hydrogel represents a mechanobiology approach for effectively restoring large bone defects through the dynamic DO process.

Keyphrases

bone mineral density
bone regeneration
drug delivery
reduced graphene oxide
hyaluronic acid
quantum dots
soft tissue
bone loss
wound healing
carbon nanotubes
solid phase extraction
postmenopausal women
highly efficient
extracellular matrix
pseudomonas aeruginosa
aqueous solution
staphylococcus aureus
cell adhesion