Intraspecies interactions of Streptococcus mutans impact biofilm architecture and virulence determinants in childhood dental caries.
Stephanie S MomeniXixi CaoBaotong XieKatherine RaineyNoel K ChildersHui WuPublished in: bioRxiv : the preprint server for biology (2023)
strains exhibit increased cell density and acidity, with individual strains occupying distinct domains. These insights, enhanced by use of time-lapsed Confocal Laser Scanning Microscopy and a Drosophila model, offer a deeper understanding of ECC pathogenesis and potential avenues for targeted interventions.
Keyphrases
- biofilm formation
- escherichia coli
- candida albicans
- pseudomonas aeruginosa
- staphylococcus aureus
- high resolution
- optical coherence tomography
- high speed
- single cell
- single molecule
- physical activity
- cell therapy
- cancer therapy
- cystic fibrosis
- high throughput
- electron microscopy
- risk assessment
- human health
- raman spectroscopy
- stem cells
- antimicrobial resistance
- label free
- young adults
- childhood cancer
- climate change