Intratracheal cobinamide (vitamin B 12 analog) administration increases survivability in rabbits exposed to a lethal dose of inhaled hydrogen sulfide.

We demonstrated that intratracheal cobinamide and fast saline drip improved survival for hydrogen sulfide gas inhalation in rabbit models. Although further study is required, our results suggest that intratracheal administration of cobinamide and fast saline may be useful in hydrogen sulfide mass-casualty events.