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Impaired Intracellular Calcium Buffering Contributes to the Arrhythmogenic Substrate in Atrial Myocytes From Patients With Atrial Fibrillation.

Funsho E FakuadeDominik HubrichtVanessa MöllerIzzatullo SobitovAiste LiutkuteYannic DöringFitzwilliam SeibertzMarcus GerloffJulius Ryan D ProntoFereshteh HaghighiSören BrandenburgKhaled AlhussiniNadezda IgnatyevaYara BonhoffStefanie KestelAschraf El-EssawiAhmad Fawad JebranMarius GroßmannBernhard C DannerHassina BarakiConstanze SchmidtSamuel SossallaIngo KutschkaConstanze BeningChristoph MaackWolfgang A LinkeJordi HeijmanStephan E LehnartGeorge KensahAntje EbertFleur E MasonNiels Voigt
Published in: Circulation (2024)
release events and AF susceptibility. Strategies targeting intracellular buffering may represent a promising therapeutic lead in AF management.
Keyphrases
  • atrial fibrillation
  • reactive oxygen species
  • left atrial
  • catheter ablation
  • heart failure
  • cancer therapy
  • amino acid
  • drug delivery
  • mitral valve
  • structural basis