Crucial Genes in Aortic Dissection Identified by Weighted Gene Coexpression Network Analysis.

Hongliang ZhangTingting ChenYunyan ZhangJiangbo LinWenjun ZhaoYangyang ShiHuichong LauYang ZhangMinjun YangCheng XuLijiang TangBaohui Xu Jianjun Jiang Xiaofeng Chen

Published in: Journal of immunology research (2022)

Our analysis provides the possible association of specific genes and gene modules for the involvement of the immune system in aortic dissection. AGFG1, MCEMP1, IRAK3, KCNE1, and CLEC4D in module M37 were highly connected and strongly linked with AD, suggesting that these genes may help understand the pathogenesis of aortic dissection.

Keyphrases

aortic dissection
network analysis
genome wide identification
genome wide
genome wide analysis
transcription factor
copy number
bioinformatics analysis
dna methylation
magnetic resonance
computed tomography
contrast enhanced