Obesity risk is associated with brain glucose uptake and insulin resistance.

Laura PekkarinenTatu KantonenEleni RebelosAino Latva-RaskuPrince DadsonTomi KarjalainenMarco BucciKari KalliokoskiKirsi LaitinenNoora HouttuAnna K KirjavainenJohan RajanderTapani RönnemaaLauri NummenmaaPirjo Nuutila

Published in: European journal of endocrinology (2022)

Increased BGU, alterations in insulin action in the brain-liver axis and decreased whole-body insulin sensitivity occur early in pre-obese state.

Keyphrases

insulin resistance
type diabetes
metabolic syndrome
adipose tissue
weight loss
resting state
white matter
high fat diet induced
high fat diet
glycemic control
functional connectivity
skeletal muscle
cerebral ischemia
blood glucose
weight gain
multiple sclerosis
blood pressure
obese patients
physical activity