Ketamine administration for acute painful sickle cell crisis: A randomized controlled trial.
Mohammed Saeed Saad AlshahraniAmal H AlSulaibikhMohamed R ElTahanSukayna Z AlFarajLaila Perlas AsontoAbdullah A AlMulhimMurad F AlAbbadNisreen AlmaghrabyMohammed Al JumaanThamir O AlJunaidMoath N DarweeshFaisal M AlHawajAlaa M MahmoudBader K AlossaimiShaikhah K AlotaibiTalal M AlMutairiDuaa A AlSulaiman PharmDDunya AlfarajReem AlhawwasStefan D BaralKim LewisMadeleine M VerhovsekMark CrowtherGordon GuyattWaleed Alhazzaninull nullPublished in: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine (2021)
Early use of ketamine in adults with VOC resulted in a meaningful reduction in pain scores over a 2-h period and reduced the cumulative morphine dose in the ED with no significant drug-related side effects in the ketamine-treated group.