Interactions of optic radiation lesions with retinal and brain atrophy in early multiple sclerosis.

Ting-Yi LinClaudia ChienJoseph KuchlingSusanna AsseyerSeyedamirhosein MotamediJudith Bellmann-StroblTanja Schmitz-Hübsch Klemens Ruprecht Alexander Ulrich Brandt Hanna Gwendolyn Zimmermann Friedemann Paul

Published in: Annals of clinical and translational neurology (2023)

Faster GCIPL thinning rate is associated with increased OR lesion load. Our results support the value of GCIPL as a sensitive biomarker reflecting both posterior visual pathway pathology and global brain neurodegeneration.

Keyphrases

multiple sclerosis
white matter
optical coherence tomography
resting state
functional connectivity
optic nerve
diabetic retinopathy
cerebral ischemia
brain injury