Short-term effect on the ocular circulation induced by unilateral intravitreal injection of aflibercept in age-related maculopathy.

Intravitreal injection of aflibercept (IVA) led to a short-term reduction in perfusion only in the treated eye. This was independent from IOP, indicating a direct pharmacological effect. No changes in choroidal perfusion were observed during the first 45 min after the injection.