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HCV kinetic and modeling analyses project shorter durations to cure under combined therapy with daclatasvir and asunaprevir in chronic HCV-infected patients.

Laetitia CaniniMichio ImamuraYoshiiku KawakamiSusan L UprichardScott J CotlerHarel DahariKazuaki Chayama
Published in: PloS one (2017)
Modeling early HCV kinetics under DCV/ASV predicts that most patients would achieve cure with short treatment durations, suggesting that 24 weeks of DCV/ASV treatment can be significantly shortened.
Keyphrases
  • hepatitis c virus
  • human immunodeficiency virus
  • newly diagnosed
  • ejection fraction
  • prognostic factors
  • replacement therapy
  • bone marrow
  • patient reported outcomes
  • cell therapy
  • gestational age