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Pulmonary Immune-Related Adverse Events of PD-1 Versus PD-L1 Checkpoint Inhibitors: A Retrospective Review of Pharmacovigilance.

Ugochi EbinamaAjay SheshadriKartik AnandIyer Swaminathan
Published in: Journal of immunotherapy and precision oncology (2023)
Using a pharmacovigilance database, we found an increased risk of multiple pulmonary irAEs after ICI therapy, particularly with PD-1 inhibitors. Further work is needed to investigate the incidence of pulmonary irAEs other than pneumonitis.
Keyphrases
  • pulmonary hypertension
  • adverse drug
  • dna damage
  • emergency department
  • cell cycle
  • rheumatoid arthritis
  • oxidative stress
  • cell therapy