Cost-minimization analysis of GSTP1c.313A>G genotyping for the prevention of cisplatin-induced nausea and vomiting: A Bayesian inference approach.

Lígia Traldi MacedoVinicius Eduardo FerrariJuliana CarronEricka Francislaine Dias CostaLeisa Lopes-AguiarGustavo Jacob LourençoCarmen Silvia Passos Lima

Published in: PloS one (2019)

GSTP1 c.313A>G genotyping may reduce the use of preventive support for chemotherapy induced nausea and lower the overall cost of treatment. Despite the results of this simulation, randomized, interventional studies are required to control for known and unknown confounders as well as unexpected expenses.

Keyphrases

chemotherapy induced
genome wide
high throughput
double blind
open label
single cell
genetic diversity
placebo controlled
phase iii
phase ii
gene expression
clinical trial
virtual reality