Dual Nickel and Brønsted Acid Catalysis for Hydroalkenylation.

Published in: Angewandte Chemie (International ed. in English) (2018)

A highly regioselective hydroalkenylation of imines or aldehydes with styrene derivatives was realized by dual catalysis with Ni(cod)2 /PCy3 and either TsNH2 or PhB(OH)2 . This process provides an atom-, step-, and redox-economic pathway towards synthetically useful allylic amines and alcohols, and opens up a new avenue for the design of more versatile coupling reactions.

Keyphrases

electron transfer
metal organic framework
visible light
room temperature
reduced graphene oxide
gold nanoparticles
transition metal
ionic liquid