Elemental Diet Enriched with Amino Acids Alleviates Mucosal Inflammatory Response and Prevents Colonic Epithelial Barrier Dysfunction in Mice with DSS-Induced Chronic Colitis.
Di GuoJun YangFangmei LingLei TuJunrong LiYi-Dong ChenKaifang ZouLiangru ZhuXiao-Hua HouPublished in: Journal of immunology research (2020)
We showed that ED amino acids can be an effective immunomodulatory agent to reduce colitis-related inflammation by inhibiting proinflammatory mediators and Th1/Th17 cell responses and by repairing the disrupted epithelial barrier.
Keyphrases
- amino acid
- ulcerative colitis
- inflammatory response
- oxidative stress
- diabetic rats
- drug induced
- emergency department
- single cell
- high glucose
- mouse model
- physical activity
- lipopolysaccharide induced
- signaling pathway
- cell therapy
- weight loss
- lps induced
- high fat diet induced
- toll like receptor
- stem cells
- skeletal muscle
- immune response
- type diabetes
- resting state
- functional connectivity