Dose Reduction in Brain [18F]FDG PET/MRI: Give It Half a Chance.

A reduction of the [18F]FDG dose down to 1 MBq/kg is possible when performing 20-min brain PET/MRI without modifying diagnostic performance and quantitative assessments. The advantage is a significant reduction in the patient effective dose, which is non-negligible in longitudinal follow-up studies and in research protocols involving healthy volunteers.