Aberrant Brain Dynamics in Schizophrenia During Working Memory Task: Evidence From a Replication Functional MRI Study.

Feiwen WangZhening LiuSabrina D FordMengjie DengWen ZhangJie Yang Lena Palaniyappan

Published in: Schizophrenia bulletin (2023)

Schizophrenia is characterized by a load-dependent reduction of stable centrality in SMA; this relates to the severity of positive symptoms, especially disorganized behaviour. Restoring SMA stability in the presence of cognitive demands may have a therapeutic effect in schizophrenia.

Keyphrases

working memory
bipolar disorder
magnetic resonance imaging
attention deficit hyperactivity disorder
contrast enhanced
resting state
sleep quality
functional connectivity
blood brain barrier