Inhibition of monocyte-like cell extravasation protects from neurodegeneration in DBA/2J glaucoma.

Pete A WilliamsCatherine E BraineKrishnakumar KizhatilNicole E FoxworthNicholas G TolmanJeffrey M HarderRebecca A ScottGregory L SousaAlyssa PanitchGareth R HowellSimon W M John

Published in: Molecular neurodegeneration (2019)

These data demonstrate a key role of monocyte-like cell extravasation in glaucoma and demonstrate that modulating neuroinflammatory processes can significantly lessen optic nerve injury.

Keyphrases

optic nerve
single cell
cell therapy
dendritic cells
optical coherence tomography
endothelial cells
peripheral blood
signaling pathway
machine learning
immune response
mesenchymal stem cells
deep learning
cataract surgery