Binding and avidity signatures of polyclonal sera from individuals with different exposure histories to SARS-CoV-2 infection, vaccination, and Omicron breakthrough infections.

Gagandeep SinghAnass AbbadJohnstone TcheouDemodara Rao MenduAdolfo Firpo-BetancourtCharles GleasonKomal SrivastavaCarlos Cordon CardoViviana SimonFlorian KrammerJuan Manuel Carreño

Published in: The Journal of infectious diseases (2023)

The magnitude and quality of the antibody response increased with the number of antigen exposures, including breakthrough infections. However, cross-reactivity of the antibody response after BA.1 breakthroughs, was impacted by the number of prior antigenic exposures.

Keyphrases

air pollution
genome wide
transcription factor
dna methylation
binding protein
coronavirus disease
respiratory syndrome coronavirus