Can neoadjuvant chemotherapy improve survival in stage T3-4N1 nasopharyngeal carcinoma? A propensity matched analysis.

Lei WangZheng WuDehuan XieShaowen LvLiangping XiaYong Su

Published in: Radiation oncology (London, England) (2020)

Additional NCT is not associated with improved survival outcomes for patients with stage T3-4N1 NPC, but bring increased hematological Grade 3-4 AEs. PLNC is independent prognostic factor in stage T3-4N1 NPC, with positive PLNC correlating with poor survival outcomes.

Keyphrases

neoadjuvant chemotherapy
prognostic factors
locally advanced
lymph node
sentinel lymph node
squamous cell carcinoma
radiation therapy
early stage
rectal cancer