IL-23R variant rs11805303 is associated with susceptibility to the development of cutaneous leishmaniasis in Leishmania guyanensis-infected individuals.
Lener Santos da SilvaJosé do Espírito SantoTirza Gabrielle Ramos de MesquitaVeronica Alice Marinho SantosJosué Lacerda de SouzaFelipe Jules de AraújoCláudio Marcello da SilveiraCilana Chagas da SilvaKrys Layane Guimarães Duarte QueirozHéctor David Graterol SequeraMarcus Vinitius de Farias GuerraMara Lúcia Gomes de SouzaRajendranath RamasawmyPublished in: The Journal of infectious diseases (2021)
The present association of the IL-23R variant rs11805303 with the development of cutaneous leishmaniasis suggests that the IL-17/IL-23 axis may play an important role in the pathogenesis of CL.
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