The effects of microenergy acoustic pulses on an animal model of obesity-associated stress urinary incontinence. Part 1: Functional and histologic studies.
Bohan WangYajun RuanTie ZhouLin WangHuixi LiDongyi PengAmanda B Reed-MaldonadoMelissa T SanfordYung-Chin LeeJun ZhouHsun Shuan WangLia BanieGuifang WangJihong LiuGuiting LinTom F LuePublished in: Neurourology and urodynamics (2019)
Obesity impairs the function of both the urethral sphincter and the pelvic floor and leads to atrophy and distortion of the striated muscle in obese female rats. These issues contribute to OA-SUI. MAP improves continence by stimulating muscle regeneration and nerve innervation as well as by activating satellite cells.
Keyphrases
- weight loss
- metabolic syndrome
- insulin resistance
- urinary incontinence
- type diabetes
- skeletal muscle
- induced apoptosis
- high fat diet induced
- weight gain
- bariatric surgery
- stem cells
- adipose tissue
- signaling pathway
- cell cycle arrest
- robot assisted
- body mass index
- case control
- endoplasmic reticulum stress
- cell death
- minimally invasive
- oxidative stress
- high density
- wound healing