M2 macrophages and regulatory T cells in lethal prostate cancer.

Ann ErlandssonJessica CarlssonMarie LundholmAnna FältSven-Olof AnderssonOve AndrénSabina Davidsson

Published in: The Prostate (2018)

Our data showed that men with high numbers of M2 macrophages in the prostate tumor environment had increased odds of dying of PCa. It is possible that M2 macrophages, together with other suppressor cells such as Tregs , promote an immunosuppressive environment.

Keyphrases

prostate cancer
regulatory t cells
induced apoptosis
radical prostatectomy
dendritic cells
palliative care
cell cycle arrest
electronic health record
big data
signaling pathway
cell proliferation
data analysis