Occurrence and Prognostic Value of Perineural Invasion in Esophageal Squamous Cell Cancer: A Retrospective Study.
Long ZhangJinchen ShaoZhichao LiuJie PanBin LiYang YangYi HeYuchen HanZhi-Gang LiPublished in: Annals of surgical oncology (2021)
PNI correlates with, and may be a concomitant consequence of, LVI and advanced tumor invasion (T3-4) in ESCC patients. Although PNI was not identified as an independent prognostic indicator, our results suggest ESCC patients with PNI should be considered for adjuvant therapy.