A Bayesian data fusion based approach for learning genome-wide transcriptional regulatory networks.
Elisabetta SautaAndrea DemartiniFrancesca VitaliAlberto RivaRiccardo BellazziPublished in: BMC bioinformatics (2020)
This Bayesian omics-data fusion based methodology allows to gain a genome-wide picture of the transcriptional interplay, helping to unravel key hierarchical transcriptional interactions, which could be subsequently investigated, and it represents a promising learning approach suitable for multi-layered genomic data integration, given its robustness to noisy sources and its tailored framework for handling high dimensional data.