Cytogenetic abnormalities and TP53 and RAS gene profiles of childhood acute lymphoblastic leukemia in Morocco.

Hanaa SkhounMeriem El FessikhMohamed El Alaoui Al AbdallaouiMohammed KhattabAziza BelkhayatZahra Takki ChebihiAmale HassaniRachid AbilkassemAomar AgadrNadia DakkaJamila El Baghdadi

Published in: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie (2024)

Our findings emphasize the significance of detecting chromosomal abnormalities as relevant prognostic markers. We also suggest a low occurrence of genetic variants among Moroccan children with ALL.

Keyphrases

acute lymphoblastic leukemia
copy number
young adults
risk assessment
allogeneic hematopoietic stem cell transplantation
genome wide
wild type
genome wide identification
childhood cancer
dna methylation
transcription factor